Back to Journals » International Journal of Chronic Obstructive Pulmonary Disease » Volume 20
ISSN: 1178-2005
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Archive: Volume 20, 2025
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- Personalizing self-management interventions in COPD – Tailoring towards individual preferences, needs, competences, disease characteristics and comorbidities (19)
- Promoting Optimized Health Care for Individuals with COPD in the Era of Telehealth (6)
- Precision Medicine in COPD (12)
- Sarcopenia and frailty in COPD: Mechanisms, Biomarkers, and Potential Interventions (3)
- Current insights and future trends for inhalation therapy in chronic obstructive respiratory disease (3)
Lung Health of Early COPD (LHEC): A Multi-Center Cohort Study—Rational and Design
Li W, Lei J, Li B, Tang X, Peng Y, Huang K, Yang T
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2561-2568
Published Date: 19 July 2025
Major Adverse Cardiovascular Events and Cause-Specific Mortality After Hospitalisation in COPD
Ioannides AE, Whittaker HR, Quint JK
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2549-2560
Published Date: 19 July 2025
Long-Term Effects of COVID-19 on Chronic Obstructive Pulmonary Disease
Lee CT, Wang PH, Cheng SL
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2539-2548
Published Date: 18 July 2025
Upregulation of ARHGAP18 by miR-613 Inhibits Cigarette Smoke Extract-Induced Apoptosis and Epithelial-Mesenchymal Transition in Bronchial Epithelial Cells
Fu H, Liu K, Zheng Y, Zhao J, Xie T, Ding Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2525-2537
Published Date: 18 July 2025
A Systematic Literature Review of the Humanistic, Economic, Sociodemographic, and Environmental Burden Associated with Severe COPD
Vlachaki I, Donhauser S, Wise RA, Chen Y, Madoni A, Scaffidi Argentina U, Mir JN, Quint JK
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2493-2523
Published Date: 17 July 2025
Association Between Advanced Lung Cancer Inflammation Index and Mortality in US Adults with Chronic Obstructive Pulmonary Disease
Su X, Rao H, Zhao C, Zhang X, Li D
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2481-2492
Published Date: 18 July 2025
Support and Its Effect for Persons Affected by COPD and Their Next of Kin - an Systematic Integrative Review
Johansson H, Jonasson LL, Berterö C
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2459-2480
Published Date: 18 July 2025

Frailty in COPD: Clinical Impact, Diagnosis, Biomarkers, and Management Strategies
Azhimamatova R, Salieva RS, Zalova TB, Karimova K, Karimova DS, Dyikanova SA, Kalmatov R, Tynaliev UM
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2445-2458
Published Date: 15 July 2025
Association Between Lactic Dehydrogenase-to-Albumin Ratio and Short-Time Mortality in Patients with Chronic Obstructive Pulmonary Disease
Yao X, Xue H, Luo J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2435-2444
Published Date: 15 July 2025
The Dietary Inflammatory Index (DII) and COPD: A Cross-Sectional Study from the NHANES
Luo ZJ, Yang H, Wang Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2423-2434
Published Date: 14 July 2025
Low-Density Lipoprotein Cholesterol as a Protective Factor in COPD and Implications for Statin Therapy: A Multi-Omics Genetic Epidemiology Study
Du T, Cao J, Dai Z, Xie X, Zhang G, Li Y, Chen B, Xu T, Feng J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2409-2422
Published Date: 14 July 2025
Acupuncture for Chronic Obstructive Pulmonary Disease: A 38-Year Bibliometric Landscape of Global Research Trends and Knowledge Evolution (1986–2024)
Wu K, Ruan C
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2393-2408
Published Date: 14 July 2025
Characteristics and Quality of Life of Patients with COPD with Different Degrees of Exercise-Induced Desaturation on Six-minute Walk Test
Gao B, Wang S, Zhao L, Liao H, Qumu S, Wang P, Yang T, Jiang S
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2381-2391
Published Date: 14 July 2025
Novel Laser System-Assisted CT-Guided Percutaneous Transthoracic Lung Biopsy in Patients with COPD Combined with Pulmonary Nodules
Li C, Hu X, Li C, Jiang G, Jiang YL
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2371-2379
Published Date: 12 July 2025
Effect of Telemonitoring on Moderate and Severe Exacerbations in Patients with COPD: Pooled Analysis of Two Randomized Controlled Trials in Denmark
Hyldgaard C, Ringbæk T, Andersen FD, Hansen EF, Jensen MS, Fenger-Grøn M, Trolle C, Ulrik CS
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2361-2369
Published Date: 11 July 2025
Factors Associated with Initial Treatment Failure in Inpatients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cohort Study
Kohyama N, Hirai K, Sagara H, Sato MT, Ohbayashi M, Kogo M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2349-2360
Published Date: 10 July 2025
Long COVID in Elderly COPD Patients: Clinical Features, Pulmonary Function Decline, and Proteomic Insights
Li S, Zhao H, Zhang M, Yuan T, Chai D, Shen Z, Qin C, Li Y, Pan M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2337-2347
Published Date: 8 July 2025
The Association Between Daily Step Count, Step Frequency and the Risk of Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study Using NHANES Data
Yuan L, Tian Z, Jia X, Chen Z
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2325-2335
Published Date: 8 July 2025
Predictors of Clinical Stability and Mortality in COPD: A Longitudinal Study
Loo WTW, Chew SY, Tan JHY, Soh RY, Koh MS, Lapperre TS, Tiew PY
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2311-2324
Published Date: 7 July 2025
Chronic Marijuana Use and Chronic Obstructive Pulmonary Disease: A Case Report
Ostertag BS, Hendrickson KW
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2305-2309
Published Date: 7 July 2025
The Crucial Role of the PPAR Signaling Pathway in the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease: An Analysis of Gene Expression and Macrophage Polarization
Zhang L, Guo R, Wu H, Abudusalamu A, Ding W, Li D, Wei X, Niu L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2287-2304
Published Date: 7 July 2025
Prompt versus Delayed Triple Therapy in COPD: Solutions to Time-Related Biases in Observational Studies
Suissa S, Dell’Aniello S, Webster-Clark MA, Ernst P
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2273-2285
Published Date: 5 July 2025
Potential Causal Relationship Between Chronic Obstructive Pulmonary Disease and Diabetes: A Bidirectional Two-Sample Mendelian Randomization Study
Wang X, Chen X, Feng R, Jiang H, Liu W
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2259-2272
Published Date: 4 July 2025
Adolescent and Current Exercise Habits in Chronic Obstructive Pulmonary Disease: Associations with Body Composition, Physical Activity, and Pulmonary Function
Iriyama T, Matsuo Y, Tsunoda Y, Yamazaki A, Uchida Y, Nakagawa H, Kinose D, Yamaguchi M, Nakano Y, Ogawa E
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2249-2257
Published Date: 4 July 2025
Exploring the Mechanisms of Lijin Fang on Treg/Th17 Cell Imbalance in COPD Based on Network Pharmacology
Li ZH, Chen SN, Pan L, Liu R, Liang W, Luo MQ, Liao HF, Feng J, Wang HZ, Huang YG, Zheng JH
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2227-2247
Published Date: 5 July 2025
Effective-Component Compatibility of Bufei Yishen Formula III Protects Lung Air-Blood Barrier by Regulating the Oxidative Stress: via the Nuclear Factor-E2-Related Factor 2 Pathway
Xu K, Shao X, Lu R, Liao Y, Zhao Y, Wang B, Qiu Z, Tian Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2211-2226
Published Date: 4 July 2025

Impact of Low Hand Grip Strength on Quality of Life, Utilization of Healthcare, and Mental Health in Individuals with Airflow Limitation
Kim SH, Zo S, Kong SA, Cho JH, Do JG, Shin SH, Park HY
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2199-2210
Published Date: 4 July 2025
Relationship Between Social Support, Symptom Burden, Dyspnea, Perceived Stress, Perceived Stigma, Coping Styles, and Psychological Distress in Patients with Stable COPD: A Structural Equation Model
Tian X, Yi L, Liu X, Zuo F, Shang H, Zhang J, Ren Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2183-2198
Published Date: 3 July 2025

CD27 on IgD-CD38-B Cells Mediates the Coprococcus-COPD Link
Gao Y, Chen L, Zhang J, Wen Z
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2173-2182
Published Date: 3 July 2025
Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening
Li W, Wen Y, Fan Y, Hu Z, Deng Z, Huang Q
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2161-2171
Published Date: 2 July 2025

Efficacy and Safety of Biologics Targeting Type 2 Inflammation in COPD: A Systematic Review and Network Meta-Analysis
Li S, Yi B, Wang H, Xu X, Yu L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2143-2159
Published Date: 3 July 2025
Sub-Optimal Chronic Obstructive Pulmonary Disease (COPD) Management in India: Findings from a Community-Based Study
Jarhyan P, Hutchinson A, Khatkar R, Prabhakaran D, Mohan S
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2131-2142
Published Date: 30 June 2025

Comorbidities and Cause of Death in COPD Patients Compared to Non-COPD Controls: An 8-year Observational Retrospective Healthcare Claims Database Cohort Study
Vogelmeier CF, Friedrich FW, Timpel P, Kossack N, Diesing J, Pignot M, Abram M, Gediga M, Halbach M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2117-2130
Published Date: 27 June 2025
In Silico Lung Deposition Profiles of Three Single-Inhaler Triple Therapies in Patients with COPD Using Functional Respiratory Imaging
Singh D, Roche N, Wu L, Sadafi H, De Backer J, Monshi Tousi N, Marshall J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2103-2116
Published Date: 27 June 2025
Incidence and Risk Factors of Tuberculosis-Associated Chronic Obstructive Pulmonary Disease
Joo DH, Kim MC, Sin S, Kang HR, Song JH, Kim HJ, Song MJ, Kwon BS, Kim YW, Lee YJ, Park JS, Lee JH, Lee YJ
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2091-2102
Published Date: 26 June 2025
Chronic Obstructive Pulmonary Disease and the Management of Cardiopulmonary Risk in the UK: A Systematic Literature Review and Modified Delphi Study
Shrikrishna D, Steer J, Bostock B, Dickinson SW, Piwko A, Ramalingam S, Saggu R, Stonham CA, Storey RF, Taylor CJ, Thakkar R, Gale CP
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2073-2090
Published Date: 25 June 2025
How Does Disease Severity Affect Clinical Outcomes and Economic Burden of Patients with COPD —— A Retrospective Population-Based Cohort Study in Tianjin, China
Wang L, Huang K, He X, Zhang J, Yang T, Wu J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2061-2072
Published Date: 25 June 2025
The Interface of a Leaky Gut with Reduced Sarcopenia-Related Quality of Life (SarQoL) in Patients with Chronic Obstructive Pulmonary Disease
Qaisar R, Karim A, Muhammad T, Ahmad F, Marinho DA, Arkadianos I, Alkahtani S
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2049-2059
Published Date: 24 June 2025
How People with COPD Perceive and Communicate Exacerbations: A Multicountry Survey Study
Franssen FME, Young R, van Boven JFM, Crooks MG, Eckerd M, Grobert M, Hurst JR, Hutchinson A, Linnell J, Stolz D, Winders T, Zhang J, El Khoury J, Nordon C
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2035-2048
Published Date: 24 June 2025
The Role and Clinical Significance of Vitamin D in Chronic Obstructive Pulmonary Disease
Sun M, Qian Y, Cai C, Zhang J, Qi R, Ma H, Ding Q, Wang S, Lv D
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2023-2033
Published Date: 23 June 2025
Cost-Effectiveness of Single-Inhaler Versus Multiple-Inhaler Triple Therapy in COPD: A German Healthcare Perspective
Beeh KM, Claussen J, Shah D, Martin A, Kendall R, Dasari P, Ismaila AS, Noorduyn SG
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2011-2022
Published Date: 19 June 2025
Withholding of Life-Sustaining Treatment and Mortality in ICU Patients with Severe Acute COPD Exacerbations: A Retrospective French Cohort
Puechoultres P, Jamme M, Abi-Abdallah G, Diop S, Legriel S, Ferré A
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1995-2009
Published Date: 18 June 2025
The Impact of Gut Microbiota on Chronic Obstructive Pulmonary Disease: A Dual-Sample Mendelian Randomization Study
Niu N, Zhao J, Li H, Miao Y, Chen F, Liu J, Cao L, Ji T, Gao F, Xie S, Zhang Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1983-1993
Published Date: 17 June 2025
Dual Use of Electronic Cigarettes and Cigarettes Elevates Risk of Chronic Obstructive Pulmonary Disease and Mental Health Issues: Insights from a Korean Health Survey
Kim CY, Park SH, Seong Y, Choi YJ, Park HJ, Cho JH, Byun MK
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1973-1981
Published Date: 17 June 2025

Paradigm Shift in the Treatment of Chronic Obstructive Pulmonary Disease Improves Patient Outcomes
Huang YJ, Wang KY, Chien WC, Chung CH, Kao LT, Kao S, Chian CF
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1965-1972
Published Date: 17 June 2025

Relationship Between COPD Progression and Frailty Progression: A Five-year Observation in Real Clinical Practice
Nishimura K, Kusunose M, Shibayama A, Nakayasu K
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1955-1964
Published Date: 14 June 2025
A Systematic Review and Meta-Analysis on the Safety and Efficacy of Rosuvastatin as an Adjunctive Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease
An WW, Zheng LT, Dong F, Zhong XN
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1939-1954
Published Date: 12 June 2025

Association of Patient-Reported Outcome Patterns and Major Clinical Factors with Frailty in Stable COPD
Yang M, Wang Z, Zhao Y, He J, Lin D, Wang Y, Liu Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1927-1937
Published Date: 12 June 2025
Association Between C-Reactive Protein to Lymphocyte Ratio and Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study
Ao T, Huang Y, Zhen P, Hu M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1915-1925
Published Date: 12 June 2025
COTE and Pulmonary Comorbidities Predict Moderate-to-Severe Acute Exacerbation and Hospitalization in COPD
Chen Q, Wang X, Yao X, Zhang L, Liu X
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1893-1913
Published Date: 11 June 2025
Influence of Urinary Incontinence Related Factors on Health-Related Quality of Life in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study
Alrajhi NS, Albarrati A, Aldhahi MI, Gwada RF
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1881-1892
Published Date: 12 June 2025
Hub Genes PRPF19 and PPIB: Molecular Pathways and Potential Biomarkers in COPD
Zhao J, Ge X, Li H, Jing G, Ma W, Fan Y, Chen J, Zhao Z, Hou J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1865-1880
Published Date: 11 June 2025
Characteristics and Outcomes of People With COPD Who Experience Exacerbations While on Inhaled Triple Therapy: Results of the SIRIUS I Cohort Study in the US (2015–2019)
Nordon C, Carstens D, Fagerås M, Müllerová H, Veeranki PS, Alves JA, Germack HD, Barnes TL, McCormack MC
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1851-1864
Published Date: 11 June 2025
FFMI: A Pivotal Indicator Bridging Pulmonary, Sleep, and Systemic Factors in COPD–OSA Overlap Patients
Wang L, Shen YY, Qian RQ, Zhang XQ, Shen XR, Chen C
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1843-1849
Published Date: 10 June 2025
Burden of Exacerbations in Patients Newly Initiating an Inhaled Regimen for COPD: A Claims Analysis
Sethi S, Wan ES, Tejwani V, Lamprey C, Aggarwal K, Dixon A, Pan Y, Siddharthan T
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1829-1842
Published Date: 7 June 2025
Unveiling the Role of Cathepsins on Lung Function in Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Analysis
Zhang X, Li X, Song S, Miao C, Yan L, Xu X, Liu Q
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1819-1828
Published Date: 7 June 2025
Exercise Dysfunction and Pulmonary Rehabilitation Strategies in COPD Patients at High-Altitudes: A Review
Fan LX, Wang HJ
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1807-1817
Published Date: 5 June 2025
Reasons for Hospital Admissions in Chronic Hypercapnic COPD Patients on Long-Term Nocturnal Noninvasive Ventilation – A Prospective Observational Study
Koschel S, Stanzel SB, Kroppen D, Duiverman M, Wollsching-Strobel M, Majorski D, Berger MP, Schumacher F, Holle JF, Windisch W, Zimmermann M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1797-1806
Published Date: 4 June 2025

Quality of Care and Outcomes of Inpatients with COPD: A Multi-Center Study in China
Wang F, Wang M, Chen X, Song A, Zeng H, Chen J, Wang L, Jiang W, Jiang M, Shi W, Li Y, Zhong H, Chen R, Liang Z
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1787-1795
Published Date: 31 May 2025
Identifying Common Diagnostic Biomarkers and Therapeutic Targets between COPD and Sepsis: A Bioinformatics and Machine Learning Approach
Li X, Xiao Y, Yang M, Zhang X, Yuan Z, Zhang Z, Zhang H, Liu L, Zhao M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1761-1786
Published Date: 28 May 2025
Assessing Knowledge and Awareness of Asthma and Chronic Obstructive Pulmonary Disease Among the Iraqi Population
Alsajri AH, Al-Qerem W, Jarab A, Mohamed Noor DA, AlHishma SW, Al Meslamani AZ, Alasmari F, Hammad A, Eberhardt J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1749-1760
Published Date: 29 May 2025
Inhaled Triple Therapy with Extrafine Single Inhaler Versus Multiple Devices in Chronic Obstructive Pulmonary Disease (TRIPOLI): A Post-Authorization Retrospective Study
Cabrera César E, López García J, Vega Lizarazo DE, Benítez-Cano Gamonoso M, Segura Romero M, Sanchez Martín S, León Nieto MI, González-Segura Alsina D, Velasco Garrido JL
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1737-1747
Published Date: 27 May 2025
Real-World Effectiveness of Triple Extrafine Fixed-Dose Combination with Beclomethasone/Formoterol/Glycopyrronium on Symptoms and Lung Function in COPD: A Systematic Review and Meta-Analysis
Rogliani P, Manzetti GM, Cazzola M, Calzetta L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1723-1736
Published Date: 27 May 2025
Assessment of Preserved Ratio Impaired Spirometry (PRISm) Based on Different Definitions in the Early COPD Cohort
Dai C, Tang G, Yang H, Wu F, Deng Z, Zheng Y, Zhao N, Lu L, Wan Q, Wang Z, Peng J, Wu X, Zhou K, Cai G, Xiao S, Wen X, Yang C, Chen S, Yu S, Sun R, Zhou Y, Ran P
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1711-1722
Published Date: 26 May 2025
The Cost-Effectiveness of a Personalised Early Warning Decision Support System (The COPDPredict™ System) to Predict and Prevent Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Hall JA, Turner AM, Gkini E, Mehta R, Spiteri M, Patel N, Jowett S
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1693-1710
Published Date: 25 May 2025
A Systematic Review of Codelists to Identify Chronic Bronchitis and Emphysema in Routine Electronic Healthcare Record Data and Derivation of a Standardized Codelist for Future Research
Kwok HHY, Massen GM, Adamson AJ, Kallis C, Lahmami A, Sheikh YA, Elseddig MHE, Mutabchi N, Quint JK
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1679-1691
Published Date: 23 May 2025
Role of Digoxin in Preventing Cigarette Smoke-Induced COPD via HIF-1α Inhibition in a Mouse Model
Zhang K, Zhou F, Zhu C, Yuan L, Li D, Wang J, Lu W
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1665-1678
Published Date: 23 May 2025
Managing Small Airways Dysfunction in COPD Patients in Real Life Under Fixed Triple Combination of Beclomethasone/Formoterol/Glycopyrronium: The MASCOT Real World Evidence Study
Gogali A, Kostikas K, Kyriakopoulos C, Potonos D, Porpodis K, Tsiouprou I, Fouka E, Tryfon S, Papadopoulou E, Kipourou M, Katsoulis K
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1651-1663
Published Date: 23 May 2025
Prognostic Value of Apolipoprotein E in Predicting One-year Mortality in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Li Y, Wu Q, Li Z, Xiao Y, Wei L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1639-1650
Published Date: 23 May 2025
Weight-Adjusted Waist Index as a Novel Predictor of Chronic Obstructive Pulmonary Disease: Evidence from NHANES 2013-2018
Wang H, Chen W, Guo F, Xu Z, Luo X, Wu J, Zhu Y, Wang Z
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1625-1638
Published Date: 22 May 2025
Characterizing ECOPD Phenotypes: Associations with In-Hospital Outcomes and Immunoinflammatory Mechanisms
Wang Q, Wang L, Zhang L, Zhao C, Liu Y, Liu L, Yuan L, Feng M, Wang G, Li L, Zhang S, Yuan Y, Kang D, Zhang X
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1613-1624
Published Date: 22 May 2025
Single-Inhaler Triple Therapy in Primary Care Across Europe: Expert Panel Consensus on the Consequences of Payer-Driven Access Rules and Call to Action
Di Marco F, Shahaj O, Valipour A, Legrand B, Jommi C, Micheletto C, Vogelmeier CF, Freeman D, Kocks JWH, Alves L, Rubio MC, Peché R, Palkonen Snr S, Winders T, Roche N
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1595-1612
Published Date: 22 May 2025
Quinine Use and the Risk of Exacerbations of Chronic Obstructive Pulmonary Disease: A Nationwide Retrospective Registry Study
Vilstrup F, Sivapalan P, Eklöf J, Jordan A, Biering-Sørensen T, Sperling S, Jensen JUS
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1585-1593
Published Date: 21 May 2025
The Association Between Medication Adherence and Health-Related Quality of Life in Patients with COPD: A Cross-Sectional Study
Saja MF, Younis AS, Alzahrani LA, Alkhlassi IN, Aldakhil LS, Albayyat RM, Alnasser NA, Alokla KS, Alghamdi LA, Rashed AN, Azer SA
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1567-1583
Published Date: 21 May 2025
The Cross-Sectional Area of Erector Spinae Muscles Obtained from Chest CT Is an Independent Predictor of Death in COPD
Liu J, Li R, Li Y, Ge S, Yao S, Zhang R, Fu H, Ning P, Zhang J, Zhang M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1555-1565
Published Date: 20 May 2025
A Peptide Encoded by lncRNA HOXB-AS3 Promotes Cigarette Smoke-Induced Inflammation in Bronchial Epithelial Cells via EZH2-Mediated H3K27me3 Modification
Lin M, Zhou X, Yang Y, Xie P, Li Q, He C, Lin Q, Wei X, Ding Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1543-1553
Published Date: 20 May 2025
Comparative Efficacy of Nutritional Supplements in Modulating Lung Function and Exercise Capacity in COPD Patients: A Network Meta-Analysis
Zeng Y, He T, Ma X, Guo Q, Zhang J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1525-1541
Published Date: 17 May 2025
Pharmacovigilance Study on Adverse Events of Nicotine Replacement Therapy, Bupropion, and Varenicline in Patients with Chronic Obstructive Pulmonary Disease
Wang YD, Wang YT, Chen HH, Bao JK, Chen SM, Chen DX
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1509-1524
Published Date: 15 May 2025
Association between Prognostic Nutritional Index and Mortality Risk in Critically Ill Patients with Chronic Obstructive Pulmonary Disease: A Retrospective Study
Liu QD, Wang DX
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1493-1508
Published Date: 15 May 2025

Sputum Microbiome, Potentially Pathogenic Organisms, and Clinical Outcomes in Japanese Patients with COPD and Moderate Airflow Limitation: The Prospective AERIS-J Study
Yatera K, Wang Z, Shibata Y, Ishikawa N, Homma T, Fukushima K, Hataji O, Inoue Y, Kawabata H, Miki K, Sato K, Tobino K, Yoshida M, Ishii T, Ito R, Kobayashi T, Kawamatsu S, Compton CH, Jones PW
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1477-1492
Published Date: 14 May 2025
Albuterol Digihaler in COPD Disease Management: A Real-World Study to Assess Digihaler Inhalation Parameters, Thresholds and Their Use to Identify Deterioration in Clinical Practice
Ferguson GT, Boe A, Hill TD, Yu D, Krishnamony M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1465-1476
Published Date: 13 May 2025
Are Smart Watches Really Smart? Comparison of Blood Oxygen Saturation Values Measured by Smart Watch, Pulse Oximetry and Arterial Blood Gases in Patients with Chronic Obstructive Pulmonary Diseases
Toru Erbay Ü, Parspur ŞE, Arikan İ, Yılmaz ZY, Koçak H, Marim F, Kaya İ, Doğan M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1457-1463
Published Date: 13 May 2025
Heart Rate Recovery After Cardiopulmonary Exercise Test Predicts Acute Exacerbations in Patients with Moderate Chronic Obstructive Pulmonary Disease
Nie S, Yang A, Yuan W, Jia N, Li Y, Yu Y, Xu B, Xu Q, Wang H, He X
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1447-1456
Published Date: 12 May 2025
Obstructive Airway Disease is Associated with Increased Cardiovascular Disease Risk Independent of Phenotype: Evidence from Two Nationwide Population-Based Studies
Meng K, Zhang X, Dai H
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1435-1446
Published Date: 12 May 2025
Association Between Lactate-to-Albumin Ratio and 28-Day All-Cause Mortality in Critical Care Patients with COPD: Can Both Arterial and Peripheral Venous Lactate Serve as Predictors?
Zhao K, Zhou L, Ni Y, Tao J, Yu Z, Li X, Wang L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1419-1434
Published Date: 11 May 2025
The Impact of Case Management on Elderly Patients with Chronic Obstructive Pulmonary Disease
Li N, Wang W, Lv Y, Li C, Mu X
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1407-1417
Published Date: 8 May 2025
The Role of Computed Tomography and Artificial Intelligence in Evaluating the Comorbidities of Chronic Obstructive Pulmonary Disease: A One-Stop CT Scanning for Lung Cancer Screening
Lin X, Zhang Z, Zhou T, Li J, Jin Q, Li Y, Guan Y, Xia Y, Zhou X, Fan L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1395-1406
Published Date: 6 May 2025

Long Term Efficacy and Safety of Bronchoscopic Thermal Vapor Ablation in Patients with COPD: A Retrospective Study of 50 Patients
Pertzov B, Ben Avraham M, Priel E, Freidkin L, Rosengarten D, Kramer MR
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1387-1394
Published Date: 7 May 2025
Construction and Validation of an Early Warning Model for Predicting the 28-Day Mortality in Sepsis Patients with Chronic Obstructive Pulmonary Disease
Yu X, Jiao Z, Yang F, Xin Q
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1373-1385
Published Date: 6 May 2025
Assessing the Causal Relationship between Chronic Obstructive Pulmonary Disease and Tuberculosis: A Mendelian Randomization Study
Wang Z, Zhao S, Zhou Y, He Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1361-1371
Published Date: 5 May 2025

Effects of 12 weeks of Head-Down Strong Abdominal Breathing Training on Gait and Cognitive Function in Patients with Chronic Obstructive Pulmonary Disease
Song F, Ding K, Sun W, Huang Q, Jiang R, Xiang H, Sun M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1347-1359
Published Date: 1 May 2025
Impact of Laboratory-Derived Frailty Index on Clinical Outcomes in Critical Care Patients with COPD: A Retrospective Analysis Using the MIMIC-IV Database
Zhou Z, He Y, Wang Q, Li J, Yu Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1335-1346
Published Date: 1 May 2025
Development and Psychometric Evaluation of an Instrument to Assess Physical Activity Participation Behavior Among Chinese Patients with Chronic Obstructive Pulmonary Disease
Liao Y, Wang H, Zhan Y, Liu Y, Wang W, Ke H, Lan F, Zhi Q, Li W, Yu J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1321-1334
Published Date: 30 April 2025
Body Mass Index and Lung Function in Hospitalized Severe AECOPD Patients: Investigating Nonlinear Associations and the Role of Hemoglobin
Zhang C, Ling W, Pan H, Bai R, He L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1309-1320
Published Date: 1 May 2025

Different Properties of the Erector Spinae and Multifidus Muscles on Physical Performance in Patients With Chronic Obstructive Pulmonary Disease
Imashiro K, Nakanishi M, Minoshima Y, Kouda K, Sasaki S, Takahashi K, Asai K, Hirano T, Matsunaga K, Minakata Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1299-1308
Published Date: 29 April 2025
Knowledge of and Attitudes Towards Standard Care in Patients with COPD
Zimmermann M, von Plessen CM, Kroppen D, Stanzel SB, Berger M, Wollsching-Strobel M, Feldmeyer F, Kellner C, Mathes T, Windisch W, Majorski DS
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1287-1297
Published Date: 29 April 2025
Imaging Phenotypes Assessment by Using Quantitative Parameters for CT-Defined Subtypes of Chronic Obstructive Pulmonary Disease
Chen W, Zhu J, Ni J, Li X, Li Y, Yin W, Zhu S, Xiao Y, Wang Y, Huang H, Hu Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1279-1286
Published Date: 28 April 2025

Comparing Heterogenous Phenotypes of Chronic Obstructive Pulmonary Disease: Network Analysis and Penalized Generalized Linear Model
Koo HK, Chung SJ, Park D, Kim HC, Seo H, Kim HJ, Yoon HK, Rhee CK, Yoo KH, Kim DK
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1267-1277
Published Date: 28 April 2025
The Mechanism of Traditional Chinese Medicine and Natural Medicine in Treating Chronic Obstructive Pulmonary Disease
Li L, Liu XF, Cui ZF, Zou H, Liu SL, Wang HW
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1249-1266
Published Date: 26 April 2025
A Brief and Effective Questionnaire for COPD Screening in High-Altitude Areas
Cui J, Wang Y, Tong Y, Liao Y, Liu Y, Chai D, Xing Z, Long H, Guo Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1239-1248
Published Date: 26 April 2025
Association Between Neutrophil Percentage to Serum Albumin Ratio and in-Hospital Mortality of Patients with Chronic Obstructive Pulmonary Disease in Intensive Care Unit: A Retrospective Cohort Study
Shi Y, Shi Y, Liu Y, Wang C, Qi M, Li C
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1227-1237
Published Date: 26 April 2025
The Effects of Smoking and Airway Restriction on Subclinical Atherosclerosis
Yeşildağ M, Keskin Z, Yavşan DM, Bekci TT, Osmanoglu UO
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1217-1226
Published Date: 24 April 2025
Increased Stress Hyperglycemia Ratio Predicts Poor Clinical Outcome in Critically Ill COPD Patients: A Retrospective Study
Qiao M, Yang H, Qin M, Li Y, Wang H
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1203-1215
Published Date: 24 April 2025

Treatable Traits in Patients with Obstructive Lung Diseases in a Well-Established Asthma/COPD Service for Primary Care
Dijk L, Gerritsma YH, Van der Molen T, Pavord I, Meijer RJ, Kerstjens HAM, JWH Kocks
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1189-1201
Published Date: 23 April 2025
Association Between Physical Activity, Sedentary Behavior and Sleep Disorders in Chronic Obstructive Pulmonary Disease Patients: A Cross-Sectional Study
Ma X, Zhang Q, Gao X, Sun M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1175-1187
Published Date: 22 April 2025

Plasma Levels of CXCL9 and MCP-3 are Increased in Asthma-COPD Overlap (ACO) Patients
Escamilla-Gil JM, Torres-Duque CA, Llinás-Caballero K, Proaños-Jurado NJ, De Vivero MM, Ramirez JC, Regino R, Florez de Arco LT, Dennis R, González-García M, Caraballo L, Acevedo N
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1161-1174
Published Date: 22 April 2025
Optimizing Treatment for Hospitalized Patients with COPD: A Study on the Impact of a LINE App-Based Multidisciplinary Team Approach Targeting Pharmacological Treatment, Lifestyle Changes, and Smoking Cessation
Huang HY, Chen CL, Lin YL, Chen SC, Lee LC, Dai HM, Chiang CY, Chang YF, Lu H, Lee MR, Yang CC, Su CH, Chiang YZ, Yang MC, Shyu RY, Lan CC
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1149-1159
Published Date: 18 April 2025
A Case of Tracheal Stenosis Following Brief Intubation for an Acute Exacerbation of COPD
Li JZ, Feng Q, Liu YF, Zheng JN
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1143-1147
Published Date: 18 April 2025
Characteristics of Patients Initiated on Budesonide/Glycopyrronium Bromide/Formoterol Fumarate Single Inhaler Triple Therapy for the Treatment of Chronic Obstructive Pulmonary Disease: A Population-Based Observational Study
Deslee G, Fabry-Vendrand C, Salmi E, Poccardi N, Coriat A, Ghout I, Eteve-Pitsaer C, Adderley NJ, Leleu H
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1131-1142
Published Date: 18 April 2025
Recommendations for Improving Discharge-Related Care Following a COPD Exacerbation: An Expert Panel Consensus with Emphasis on Low- and Middle-Income Countries
Rendon A, Luhning S, Bardin P, Celis-Preciado CA, El Shazly M, Cohen-Todd M, Ismail AI, Idrees M, Lim SY, Fu PK, Seemungal T, Köktürk N, Hurst JR
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1111-1129
Published Date: 16 April 2025
Impact of a Heating Voucher on Health Outcomes in COPD Patients: A Randomised Controlled Trial
Viggers HE, Ingham TR, Chapman RB, Crane J, Currie AB, Davies C, Keall M, Howden-Chapman PL
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1097-1109
Published Date: 16 April 2025
Identification of Cuproptosis-Related Genes and Their Potential Role in COPD Pathogenesis: A Bioinformatics Analysis
Shen Q, Huang JB, Zhu M, Ji DJ, Huang SJ, Li J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1083-1096
Published Date: 15 April 2025
Exercise Prescription Training in Chronic Obstructive Pulmonary Disease: Benefits and Mechanisms
Liu S, Yang A, Yu Y, Xu B, Yu G, Wang H
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1071-1082
Published Date: 15 April 2025

Clinical Characteristics and Outcomes of Eosinophilic Exacerbations of COPD
Donnan M, Liu TL, Gvalda M, Chen X, Foo CT, MacDonald MI, Thien F
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1061-1070
Published Date: 13 April 2025
Impact of the COVID-19 Pandemic on ACO Prevalence Among AECOPD Patients (2019-2023) and Clinical Characteristics by Blood Eosinophil Levels
Zhang S, Song W, Sun T, Wu S, Wang Z, Meng A
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1051-1060
Published Date: 12 April 2025
Real-World Effectiveness of Single-Inhaler Triple Treatment Through Assorted Respiratory Outcomes When Switched From Multiple-Inhaler Triple Therapies (RESTART): A Prospective Cohort Study of Korean Patients With COPD
Lim H, Kim DH, Hong SH, Shin J, Lee H, Shin K, Ra SW, Lee SJ
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1039-1050
Published Date: 11 April 2025
Risk and Protective Factors of COPD Among Smokers: A Cross-Sectional Study Using NHANES Database
Guo X, Luo Q, Chen D, Lin H
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1027-1038
Published Date: 11 April 2025
Identification of Psychosocial and Sociodemographic Factors Associated with Low Medication Awareness in COPD Subjects: A Cross-Sectional Study, Findings from the Indonesian Family Life Survey 5
Jannah W, Alfian SD, Abdulah R
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1009-1026
Published Date: 9 April 2025
Characteristics of Patients Receiving Budesonide/Glycopyrronium/Formoterol for Chronic Obstructive Pulmonary Disease in Spain: The AURA Study
Calle Rubio M, Trigueros Carrero JA, Chaparro Briones P, Escudero Herrera L, Pollack M, Hernández Subirá I, Sánchez-Covisa J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:999-1008
Published Date: 9 April 2025
Biomarkers (NLR, PLR, SII) for Frequent COPD Exacerbations: Diagnostic and Clinical Management Implications in a Retrospective Study
Fu Y, Wang Y, Wang Y, Mou T, He X, Wang J, Xiong A, Qing B, Wu D, Li G
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:987-998
Published Date: 5 April 2025
Abnormal Brain Functional Connectivity in Patients with Chronic Obstructive Pulmonary Disease and Correlations with Clinical and Cognitive Parameters
Han KI, Yeo Y, Jo HJ, Jo MJ, Park Y, Park TS, Jung SJ, Bae JH, Jang SH, Choi J, Park DW, Kim TH
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:971-985
Published Date: 5 April 2025
Evolution of Peak Inspiratory Flow During Hospitalization of Patients with COPD – A Prospective Monocentric Observational Study
Suter P, Grobéty T, Vaucher J, Grandmaison G
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:957-969
Published Date: 4 April 2025
Sputum SLC40A1 as a Novel Biomarker is Increased in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Ju X, Chen Z, Gao L, Chen M, Wang Q, Jiang Z
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:943-955
Published Date: 2 April 2025
Evaluation of the Efficacy of Jiangqi Dingchuan Pill Based on Network Pharmacology Analysis and Cigarette Smoke and Lipopolysaccharide Induced Chronic Obstructive Pulmonary Disease Rat Model
Zhou J, Song J, Peng D, Zheng Y, Ning N, Chen G, Huang Q, Li Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:929-941
Published Date: 2 April 2025
Association Between Visceral Adipose Tissue and Chronic Respiratory Diseases: A Two-Sample Multivariable Mendelian Randomization Study in European Population
Huang JX, Xiao BJ, Yan YX, Xie W, Feng LY, Liu XM
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:919-928
Published Date: 2 April 2025
Potential of the Advanced Lung Cancer Inflammation Index as a Risk Marker for Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome and COPD: Evidence from NHANES 2007-2018
Chen N, Liu Y, Wang Q, Wang M, Wang J, Chen W
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:905-917
Published Date: 31 March 2025
Factors Influencing Compliance with Pulmonary Rehabilitation in Patients with Stable COPD: a Cross Sectional Study
Xia X, Xia K, Yao X, Song J, Liu Y, Liu X, Zhang H, Li G
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:895-904
Published Date: 31 March 2025
Association Between Urinary Glyphosate Concentrations and Chronic Obstructive Pulmonary Disease in USA Participants: Evidence from NHANES 2013–2018
Shi Y, Pu S, Huang N, Wang Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:883-894
Published Date: 31 March 2025
Elucidating the Relationship Between Body Fat Index and Pulmonary Health: Insights from Cross-Sectional Analysis and Mendelian Randomization
Zhang Q, Wang Z, Liu W, Cai G, Gao Y, Chen Y, Han Y, Nie A, Liang R, Cui F, Chen Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:869-882
Published Date: 31 March 2025
Association Between the Non-High-Density Lipoprotein Cholesterol-to-High-Density Lipoprotein Cholesterol Ratio (NHHR) and Mortality in Patients with COPD: Evidence From the NHANES 1999–2018
Zhong Y, Zhou K, Li S, Zhang R, Wang D
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:857-868
Published Date: 28 March 2025
Identification of Oxidative Stress-Associated Biomarkers in Chronic Obstructive Pulmonary Disease: An Integrated Bioinformatics Analysis
Jiang X, Wang M, Li H, Liu Y, Dong X
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:841-855
Published Date: 26 March 2025
Impact of Airway-Occluding Mucus Plugs on Mortality in Patients with COPD According to Disease Severity: A Subset Analysis of Data From COPDGene
Rogliani P, Calzetta L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:831-840
Published Date: 26 March 2025
The Impact of Age and Disease Entity on Small Airway Dysfunction in Obstructive Airway Diseases
Li Y, Su KC, Hsiao YH, Chou KT, Li YJ, Jeng TH, Ko HK, Perng DW
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:821-830
Published Date: 27 March 2025

Validation of an AI-Powered Smart Dry Powder Inhaler (RS01X) for Asthma and COPD in a Clinical Setting
Chamaon D, Sportel E, Elferink ECM, van der Palen J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:811-819
Published Date: 25 March 2025
Two-year Results of Bronchoscopic Lung Volume Reduction Using One-Way Endobronchial Valves: Real-World Single Center Data
Bivort D, Blondeel A, Geysen H, Vandervelde CM, Coolen J, Ceulemans LJ, Dooms C, Janssens W, Everaerts S
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:799-810
Published Date: 25 March 2025

Association Between Mechanical Power and 28-Day All-Cause Mortality in Chronic Obstructive Pulmonary Disease Patients Undergoing Invasive Ventilation: Analysis of the MIMIC-IV Database


Wu S, Li H, Xu J, Cai J, Wu L, Xu Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:785-797
Published Date: 24 March 2025
Associated Factors and Pulmonary Function Outcomes of Preserved Ratio Impaired Spirometry: A Scoping Review
Xu H, Jiang X, Zeng Q, Li R
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:767-784
Published Date: 24 March 2025

Dynamic Risk Status of OSA and Its Association with COPD Incidence and Progression to Oxygen Therapy: Insights from a US National Cohort


Wang Y, Luo J, Huang R, Xiao Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:753-766
Published Date: 21 March 2025

COPD Exacerbations, Air Pollutant Fluctuations, and Individual-Level Factors in the Pandemic Era
Mikaeeli S, Doiron D, Bourbeau J, Li PZ, Aaron SD, Chapman KR, Hernandez P, Maltais F, Marciniuk DD, O’Donnell DE, Sin DD, Walker BL, Tan WC, Rousseau S, Ross BA
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:735-751
Published Date: 17 March 2025
Hyperkalemia Is an Underestimated Risk Factor in COPD
Mäenpää J, Anderson I, Owen CA, Emerath U, Hughes R, Sultana SR, Olsson M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:723-734
Published Date: 15 March 2025
The Causal Relationship Between Gut and Skin Microbiota and Chronic Obstructive Pulmonary Disease:A Bidirectional Two-Sample Mendelian Randomization Analysis
Luo Z, Liao G, Meng M, Huang X, Liu X, Wen W, Yue T, Yu W, Wang C, Jiang Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:709-722
Published Date: 15 March 2025
The Impact of Beta-Blockers and Renin-Angiotensin-Aldosterone System Inhibitors on the Prognosis of Atrial Fibrillation Patients with Chronic Obstructive Pulmonary Disease: A Nation-Wide Registry Study
Liang H, Tan J, Xu W, Lyu S, Wu S, Wang J, Shao X, Zhang H, Yang Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:699-708
Published Date: 13 March 2025
Application of Discrete Event Simulation Models for COPD Management: A Systematic Review
Shuai L, Zhou C, Zhou J, Hu H, Lai Y, Fan L, Du W, Li M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:685-698
Published Date: 12 March 2025
Predictive Value of the Neutrophil-to-Lymphocyte Ratio/Serum Albumin for All-Cause Mortality in Critically Ill Patients Suffering from COPD
Liu Y, Zhao W, Hu C, Zhang Y, Qu Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:659-683
Published Date: 12 March 2025
A Novel Percutaneous Volume Reduction Technique for Giant Emphysematous Bullae: Combined Percutaneous Erythromycin Sclerotherapy With Bronchoscopic Occlusion
Wang Z, Liu Z, Zhang W, Liu W, Tan J, Li X, Wu H, Li Y, Deng H, Chen J, Chen L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:641-657
Published Date: 11 March 2025
Effective-Component Compatibility of Bufei Yishen Formula (ECC-BYF) III Inhibits Mucus Hypersecretion by BEAS-2B Cells via miR-146a-5p-Mediated Regulation of the EGFR/MEK/ERK Pathway
Wei Y, Ma J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:623-639
Published Date: 10 March 2025
Estimated Plasma Volume Status and the Risk of in-Hospital Mortality Among Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease in Intensive Care Unit: Retrospective Cohort Study from the eICU Collaborative Research Database
Guo X, Zhang L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:611-621
Published Date: 11 March 2025
Causal Associations Between Chronic Obstructive Pulmonary Disease and Common Comorbidities: Evidence from Comprehensive Genetic Methods
Ji J, Zhao Q, Yuan J, Yuan Z, Gao N
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:601-610
Published Date: 8 March 2025
Identification and Experimental Validation of Biomarkers Related to MiR-125a-5p in Chronic Obstructive Pulmonary Disease
Jing X, Li Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:581-600
Published Date: 8 March 2025

Effectiveness of Switching from Multiple-Inhaler to Once-Daily Single-Inhaler Triple Therapy in Patients with COPD in a Real-World Setting in Japan
Requena G, Camidge LJ, Ford A, Yarita M, Hashimoto K, Jennison T, Massey OS, Noorduyn SG, Mizukami A
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:565-580
Published Date: 8 March 2025
PGAM5 Modulates Macrophage Polarization, Aggravating Inflammation in COPD via the NF-κB Pathway
Zheng Y, Wang Y, Li J, Zheng S, Zhang L, Li Q, Ling F, Nie Q, Feng Q, Wang J, Jin C
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:551-564
Published Date: 6 March 2025

Signs of Hyperinflation and Ventilation Heterogeneity in Individuals With Severe Alpha-1-Antitrypsin Deficiency at the Age of 42
Schramm GR, Wollmer P, Piitulainen E, Zaigham S, Tanash H
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:539-549
Published Date: 5 March 2025

Delivery of Remote Pulmonary Rehabilitation: COVID-19 Service Evaluation in England
Ellis J, Gilworth G, Morgan T, Harris K, King N, White P
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:533-538
Published Date: 5 March 2025
Targeting Non-Eosinophilic Immunological Pathways in COPD and AECOPD: Current Insights and Therapeutic Strategies
Razia DEM, Gao C, Wang C, An Y, Wang F, Liu L, Lin H
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:511-532
Published Date: 5 March 2025
SCGB1A1 as a Key Regulator of Splenic Immune Dysfunction in COPD: Insights From a Murine Model
Chen X, Wang Q, Gong M, Wu Y, Huang X, Ye F, Huang L, Jiang S, Shi J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:497-509
Published Date: 3 March 2025
Effect of Nutritional Management on the Nutritional Status and Quality of Life of Patients with Chronic Obstructive Pulmonary Disease
Zhang JH
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:487-496
Published Date: 1 March 2025
Mucolytic Therapy in COPD: Patient Usage and Preferences in Real-World Italian Settings
D’Antonio S, Pennisi A, Cazzola M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:479-486
Published Date: 1 March 2025
Community-Based Pulmonary Rehabilitation in an Economically Deprived Area of Jodhpur, India: A Mixed-Methods Feasibility Trial
Thakor M, Singh V, Manifield J, Orme MW, Bhardwaj P, Chauhan NK, Barradell AC, Ahmed Z, Bhati Y, Matheson J, Barton A, Sharma AK, Singh SJ
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:473-478
Published Date: 28 February 2025
A Delphi Consensus Project to Capture Greek Experts’ Opinion on the Position of Triple Therapies in COPD: Why, When and to Whom
Papaioannou AI, Loukides S, Vassilakopoulos T, Tzanakis N, Kostikas K, Hillas G
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:457-471
Published Date: 26 February 2025
A Case of Pulmonary Bulla Volume Reduction by Transbronchial Puncture Under Electromagnetic Navigation Platform Combined With O-Arm CT Guidance
Zhu J, Xu X, Wang R, Li Z, Wang Y, Hu Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:451-455
Published Date: 25 February 2025
Restriction of Parameters and the Common Issue of Multicollinearity in Multivariate Analysis [Letter]
Erinç A, Kirac A, Satici C
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:449-450
Published Date: 25 February 2025
Associations of Serum Legumain with Severity and Prognosis Among Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients
Zhang QQ, Ma MM, Chen ZY, Guo YX, Liu K, Xie ML, Wang YL, Li SS, Qian H, Zhang XF, Fu L, Jiang YL
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:437-447
Published Date: 25 February 2025
Frequency of Exacerbations of Chronic Obstructive Pulmonary Disease Associated with the Long-Term Exposure to Air Pollution in the AIREPOC Cohort
Herrera Lopez AB, Torres-Duque CA, Casas Herrera A, Arbeláez MP, Riojas-Rodríguez H, Texcalac-Sangrador JL, Rojas NY, Rodriguez-Villamizar LA
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:425-435
Published Date: 22 February 2025

Cholesterol Accumulation Enhances Cigarette Smoke-Induced Airway Epithelial Inflammation


Jing D, Yu JK, Chen HP, Dong LL, Li W, Li ZY, Zhou JS
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:411-423
Published Date: 21 February 2025

Adherence to Inhalation Therapy Among COPD Patients: A Cross-Sectional Study in a Tertiary Hospital in Quito, Ecuador
Izquierdo-Condoy JS, Gualpa Álvarez F, Morales-Lapo E, Arias Calvache WD, Bermúdez Moreira J, Quinga-Chiguano KM, Ortiz-Prado E
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:399-410
Published Date: 21 February 2025
Skeletal Muscle Function in Relation to COPD Severity and Its Predictive Significance for Disease Progression
He Z, Cao B, Liu K, Wei Q
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:389-397
Published Date: 21 February 2025
Metabolic Regulation in Acute Respiratory Distress Syndrome: Implications for Inflammation and Oxidative Stress
Yue L, Yan Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:373-388
Published Date: 18 February 2025
The Miasma Mentality: Investigating the Association Between Beliefs in Noxious Fumes and Obstructive Pulmonary Disease (COPD), Symptoms, and Quality of Life
Zhao Y, Ma Y, Geng L, Nie J, Yu X, Kang Z, Liu Y, Su Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:361-372
Published Date: 19 February 2025
Association Between Blood Urea Nitrogen to Serum Albumin Ratio and Mortality in Critically Ill Patients With Chronic Obstructive Pulmonary Disease: A Retrospective Study
Li J, Peng J, Cheng C, Zhang J, Li L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:349-360
Published Date: 17 February 2025

Clinical and Economic Evaluation of Fluticasone Furoate/Umeclidinium/Vilanterol Versus Tiotropium/Olodaterol Therapy in Maintenance Treatment–Naive Patients with COPD in the US
Shaikh A, Ritz J, Casciano J, Palli SR, Clark B, Dotiwala Z, Quint JK
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:335-348
Published Date: 14 February 2025
Real-World Evaluation of an EHR-Enabled Chronic Obstructive Pulmonary Disease Assessment Test
Gaeckle N, Corazalla E, Kelloway JS, Liberman JN, Darer JD, Kahle-Wrobleski K, Paczkowski R, Parab P, Ruetsch C
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:325-334
Published Date: 14 February 2025
Diagnostic Inaccuracies in COPD: Misdiagnosis, Race and Gender Disparities
Maus SE, Norton DL, Saha AK, Wells BJ, Ohar JA
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:319-323
Published Date: 12 February 2025
Single-Use Flexible Bronchoscope in Facilitating Endobronchial Valve Treatment in Severe Emphysema
Sakaguchi T, Slebos DJ
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:313-317
Published Date: 12 February 2025
Prevalence of Myocardial Infarction With Obstructive and Non-Obstructive Coronary Arteries in a Middle-Aged Population With Chronic Airflow Limitation: A Cross-Sectional Study
Sundh J, Ekström M, Blomberg A, Lindberg E, Malinovschi A, Olin AC, Sköld CM, Torén K, Wollmer P, Östgren CJ, Jernberg T
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:303-312
Published Date: 12 February 2025
Risk of All-Cause Mortality in US Adults With Preserved Ratio Impaired Spirometry: An Observational Study
Xiao S, Ou J, Qiu W, Ye C, Li N, Chen S, Lai Y, Deng Z, Wu F, Shen Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:287-302
Published Date: 11 February 2025
Chronic Airflow Limitation, Lower Respiratory Symptoms, COPD and Chronic Rhinosinusitis in a Middle-Aged Population: The Swedish CArdioPulmonary bioImage Study (SCAPIS). A Link Between the Lower and Upper Airways
Andersson A, Bergqvist J, Schiöler L, Bossios A, Farnebo L, Holmlund T, Janson C, Keceli S, Ljunggren M, Malinovschi A, Memarian E, Nihlén U, Nilsson PM, Pesonen I, Sjöström M, Stenfors N, Sundbom F, Werner M, Torén K, Sköld M, Hellgren J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:273-286
Published Date: 11 February 2025
A Bidirectional Mendelian Randomization Study Investigating the Causal Relationship Between Ankylosing Spondylitis and Chronic Obstructive Pulmonary Disease
Pan D, Dai X, Li P, Xue L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:259-271
Published Date: 8 February 2025
The Mediation of Circulating Inflammatory Proteins in the Causal Pathway from Immune Cells to COPD
Yan K, Wang Y, Xin P
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:245-257
Published Date: 7 February 2025
Re “Inhaled Corticosteroid Particle Size and Risk of Hospitalization Rue to Exacerbations and All-Cause Mortality in Patients With Chronic Obstructive Respiratory Disease. A Nationwide Cohort Study”. Heerfordt et al [Letter]
Hubbard R, Carter V, Henley W, Price D
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:243-244
Published Date: 5 February 2025

Feasibility, Usability, and Pilot Efficacy Study of a Software-Enabled, Virtual Pulmonary Rehabilitation with Remote Therapeutic Monitoring
Flynn S, Mosher CL, Cornelison S, Rao E, Metzler KA, Pu W, Davies J, Paladenech C, Doyle D, MacIntyre N, Ohar J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:231-241
Published Date: 31 January 2025
Risk of All-Cause Mortality in Mild Chronic Obstructive Pulmonary Disease: Evidence From the NHANES III and 2007–2012
Zou W, Ou J, Wu F, Xiao S, Deng Z, Li H, Wang Z, Tang G, Liu S, Ye D, Zhu D, Hu J, Ran P
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:217-229
Published Date: 30 January 2025
Post-Acute Care Interventions in Patients Hospitalized Due to COPD Exacerbation Before and After Implementation of an Integrated Care Program
Hübsch C, Clarenbach CF, Franzen DP, Schmid-Mohler G
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:207-216
Published Date: 28 January 2025
Exploring the Causal Relationship Between Frailty and Chronic Obstructive Pulmonary Disease: Insights From Bidirectional Mendelian Randomization and Mediation Analysis
Cheng Z, Wu J, Xu C, Yan X
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:193-205
Published Date: 25 January 2025
Symptom Network and Subgroup Analysis in Patients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study
Yu C, Xu M, Pang X, Zhang Y, Cao X, Xu Y, Huang S, Zhao H, Chen C
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:181-192
Published Date: 23 January 2025
The Role of Severe Vitamin D Deficiency in Predicting the Risk of Severe Exacerbation in Patients With Chronic Obstructive Pulmonary Disease
Zhou L, Han C, Zhou Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:171-179
Published Date: 22 January 2025
The Association Between the CALLY Index and All-Cause Mortality in Patients with COPD: Results from the Cohort Study of NHANES 2007–2010
Ding Y, Liu Y, Yu J, Cai C, Fu L, Zhu J, Yang S, Jiang Y, Wang J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:159-169
Published Date: 22 January 2025
Cumulative Dispensing of Oral Corticosteroids Over 12 Months in People with COPD
Burge AT, Cox NS, Dal Corso S, Jones AW, Faqih FM, Holland AE
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:149-158
Published Date: 20 January 2025
Assessing the Clinical and Functional Status of COPD Patients Using Speech Analysis During and After Exacerbation
Mayr W, Triantafyllopoulos A, Batliner A, Schuller BW, Berghaus TM
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:137-147
Published Date: 20 January 2025
Impact of Hyponatraemia at Clinical Stable-State on Survival in Patients with Chronic Obstructive Pulmonary Disease
Kwok WC, Yap DYH, Tam TCC, Lam DCL, Ip MSM, Ho JCM
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:127-135
Published Date: 15 January 2025
Why Anemia is Associated with Increased Mortality in AECOPD, What Should We Do? [Letter]
Zhou TT
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:125-126
Published Date: 13 January 2025
High BMP7 Expression May Worsen Airway Disease in COPD by Altering Epithelial Cell Behavior
Dong W, Xie M, Ming C, Li H, Xu X, Cui L, Wang W, Li Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:107-124
Published Date: 8 January 2025
Peripheral Blood NMLR Can Predict 5-Year All-Cause Mortality in Patients with Chronic Obstructive Pulmonary Disease
Li Y, Ge S, Liu J, Li R, Zhang R, Wang J, Pan J, Zhang Q, Zhang J, Zhang M
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:95-105
Published Date: 8 January 2025
Causal Relationships Between Blood Lipid Levels and Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Analysis
Huang P, Zhao Y, Wei H, Wu W, Guo Z, Ma S, Xu M, Wang Q, Jia C, Xiang T, Li H
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:83-93
Published Date: 8 January 2025
Wnt3a Enhances Mesenchymal Stem Cell Engraftment and Differentiation in a Chronic Obstructive Pulmonary Disease Rat Model
Wu H, Zhong Y, Li Y, Zhou X, Zhao T, Wan D, Zhu Y, Zhang Z, Li X, Gan X
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:69-81
Published Date: 8 January 2025

Personalizing Self-Management Interventions in COPD – Looking Beyond One-Size-Fits-All
Lenferink A, Brusse-Keizer MG, van der Palen J, Effing TW
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:65-68
Published Date: 8 January 2025
Correlation of Aspergillus fumigatus Sensitization with Mucus Plugging in COPD
Luo Y, Ren J, Liang L, Qu J, Chang C, Sun Y
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:57-63
Published Date: 7 January 2025
Unraveling the Role of Oxygen Pulse Variability in Endurance Exercise Training in Individuals with COPD: A Novel Approach to Response of Oxygen Pulse and Quality of Life in Pulmonary Rehabilitation
Huang SY, Hsieh PC, Huang KL, Yang MC, Jao LY, Tzeng IS, Lan CC, Wu YK
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:43-56
Published Date: 7 January 2025
Research Status and Direction of Chronic Obstructive Pulmonary Disease Complicated with Coronary Heart Disease: A Bibliometric Analysis from 2005 to 2024
Bian H, Zhu S, Xing W, Qi L, Xue J, Peng X, Jin Z, Zhao H
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:23-41
Published Date: 7 January 2025
Unveiling the Prognostic Power of HRR in ICU-Admitted COPD Patients: A MIMIC-IV Database Study
Wang Y, Chen D, Zhang C, Yang H
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:11-21
Published Date: 6 January 2025
The Role of Diaphragmatic Ultrasound in Identifying Sarcopenia in COPD Patients: A Cross-Sectional Study
Yetkin NA, Akın S, Kocaslan D, Baran B, Rabahoglu B, Oymak FS, Tutar N, Gulmez İ
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1-9
Published Date: 1 January 2025