小约翰·a·波尔科教授

CMD主任，化学教授

Professor Porco received his Ph.D. in Organic Chemistry with 斯图亚特·施赖伯 at 哈佛大学 in 1992 and did postdoctoral studies in 黄志慧‘s laboratory at the 斯克里普斯新濠影汇线上赌场研究所. Dr. Porco worked as an associate for 阿瓦隆公司 where he participated in the founding of several biotechnology companies, including Pharmacopeia, Aurora Biosciences, and Argonaut Technologies. He was the first scientist at Argonaut Technologies and in 1997 was promoted to Director, Parallel Medicinal Chemistry where he and his colleagues developed a number of reagents and methods for parallel 化学合成.

Research activities in the Porco集团 involve the development of new methodologies for 化学合成 and their application to synthesis of complex 天然产物 and natural product-like molecules. 合成的目标包括具有药理活性的化合物，其中结构变体的制备将允许解剖与生物分子的调节相互作用。 利用简单的反应块和工作站进行平行合成也用于高效优化新的化学反应和关键的合成转化。