Central nervous system (CNS) lesions become surrounded by neuroprotective borders of newly proliferated reactive astrocytes; however, fundamental features of these cells are poorly understood. Here we show that following spinal cord injury or stroke, 90% and 10% of border-forming astrocytes derive, respectively, from proliferating local astrocytes and oligodendrocyte progenitor cells in adult mice of both […]
This April, Center faculty members Hadi Nia and Tim O’Shea published “Alteration of mechanical stresses in the murine brain by age and hemorrhagic stroke” in the PNAS Nexus journal. Their research works towards a better understanding of residual mechanical stresses in the brain. Also known as solid stresses, mechanical stresses develop when brain tissues grow […]
Professor Gabel et al. were recently published in eLife for their work on “O-GlcNAc signaling increases neuron regeneration through one-carbon metabolism in Caenorhabditis elegans”.
Professor Ben Scott et al. were recently published in Cell Reports for their article: “In vivo imaging in transgenic songbirds reveals superdiffusive neuron migration in the adult brain”
Nearly 800,000 Americans experience a stroke each year, making it a leading cause of disability. One common condition after a stroke is hemiparesis – muscle weakness or partial paralysis – which can make movement slower and more difficult. Walking, and in particular independent walking outside the home, poses a significant challenge for as many as 85 […]
Chosen for their Jan. 4, 2024 publication in Biomedical Optics Express, the research team’s work on “Dynamic light scattering and laser speckle contrast imaging of the brain: theory of the spatial and temporal statistics of speckle pattern evolution” was chosen for its “excellent scientific quality and [representation] of the work taking place in a specific […]
Mai-Anh T. Vu, a Post-Doc researcher in Mark Howe’s lab, shared a recent article from Howe’s lab on X this Monday. The article, titled “Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior”, was published by Ian Davidson, David Boas, and Mark Howe in ScienceDirect. The […]