新濠影汇赌场

Real-World Asthma Management: A Spotlight on Pragmatic and Observational Research

Asthma is a chronic respiratory disease affecting millions of people worldwide. While significant advances have been made in understanding asthma pathophysiology and developing treatments, managing the condition in real-world clinical practice remains a challenge. Classical randomized controlled trials (RCTs) are designed to maximize internal validity and to establish an unequivocal cause-and-effect relationship between an intervention and an outcome; however, these trials often exclude patients in minority groups, those with comorbidities, severe illness, or those that do not adhere to treatments. Consequently, there is a critical need for complementary data derived from pragmatic and observational studies that reflect the complexities of real-world asthma management.